As the immortal Demon Princess inexorably transforms Demon City Shinjuku into a vampire metropolis, Setsura infiltrates her manor house alone. There he encounters the puppet paramours and “picture soldiers” created by the warlock Kikiou.
The witch Galeen Nuvenberg once again comes to the rescue. But that only draws her into Princess’s crosshairs as well.
Meanwhile, panicked by the growing vampire hordes in Shinjuku, the Japanese government and its American allies resolve to sterilize the city with nuclear weapons. As if taunting the stranded and isolated Setsura, the countdown to disaster has begun.